Listen here EPISODE DETAILS Hosts, Andrew Marderstein and Lucia Hindorff, chat with Barbara Bitarello on her work, " Polygenic Scores for Height in Admixed Populations" and what led to her career path. Check out the written interview by visiting the ASHG website. Link to the publication which the podcast is focusing on: “Polygenic Scores for Height in Admixed Populations”
Hosts, Andrew Marderstein and Lucia Hindorff, chat with Bárbara Bitarello on her work, " Polygenic Scores for Height in Admixed Populations" and what led to her career path. Check out the written interview by visiting the ASHG website. Read the paper here: “Polygenic Scores for Height in Admixed Populations” Listen here
Listen here. Polygenic risk scores (PRS) rely on the genome-wide association studies (GWAS) to predict the phenotype based on the genotype. However, the prediction accuracy suffers when GWAS from one population are used to calculate PRS within a different population, which is a problem because the majority of the GWAS are done on cohorts of European ancestry. In this episode, Bárbara Bitarello helps us understand how PRS work and why they don’t transfer well across populations.